Summary: In an event reminiscent of eukaryotic ubiquitination, the bacterial prokaryotic ubiquitin-like protein (Pup)-proteasome system (PPS) marks target proteins for proteasomal degradation by covalently attaching Pup, the bacterial tagging molecule.Yet, ubiquitin is released from its conjugated target following proteasome binding, whereas Pup en
BACKGROUND: The aim of this study is to describe the clinical course and outcome of patients who were diagnosed with Aloe Vera acute respiratory distress syndrome (ARDS) caused by scrub typhus and who received ventilator care in the intensive care units (ICU) of two university hospitals.METHODS: We performed a retrospective analysis of all adult ve
This article presents the two phenomena of economic financial crime: corruption and the underground economy, which have managed to expend internationally.The current context has allowed the emergence and the development of this phenomena into the society, the public sector and the business environment that generates a decrease of investments, PHOSS
Background: Recognition of emotions in facial expressions (REFE) is a key aspect of social cognition.Anxiety and mood disorders are associated with deficits in REFE, and anxiolytics and antidepressants reverse these deficits.Recent studies have Point shown that serotonergic hallucinogens (i.e.ayahuasca, dimethyltryptamine, psilocybin, lysergic acid
Background: The co-existence of two genetically distinct metabolic disorders in the same patient has rarely been reported.Phenylketonuria (PKU) is an inborn error of the metabolism resulting from a phenylalanine hydroxylase defi ciency.Fabry disease (FD) is an X-linked lysosomal storage disorder due to a defi ciency of the enzyme alpha-galactosidas